SH2 domain-containing adapter protein B is a protein that in humans is encoded by the SHB gene.[5][6]

SHB
Identifiers
AliasesSHB, bA3J10.2, SH2 domain containing adaptor protein B
External IDsOMIM: 600314; MGI: 98294; HomoloGene: 74458; GeneCards: SHB; OMA:SHB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003028

NM_001033306

RefSeq (protein)

NP_003019

NP_001028478

Location (UCSC)Chr 9: 37.92 – 38.07 MbChr 4: 45.42 – 45.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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SHB (gene) has been shown to interact with:

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000107338Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044813Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yulug IG, Hillermann R, Fisher EM (Dec 1994). "The SHB adaptor protein maps to human chromosome 9". Genomics. 24 (3): 615–7. doi:10.1006/geno.1994.1681. PMID 7713524.
  6. ^ "Entrez Gene: SHB Src homology 2 domain containing adaptor protein B".
  7. ^ a b c d Karlsson T, Songyang Z, Landgren E, Lavergne C, Di Fiore PP, Anafi M, Pawson T, Cantley LC, Claesson-Welsh L, Welsh M (Apr 1995). "Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins". Oncogene. 10 (8): 1475–83. PMID 7537362.
  8. ^ Lindholm CK, Gylfe E, Zhang W, Samelson LE, Welsh M (Sep 1999). "Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells". The Journal of Biological Chemistry. 274 (39): 28050–7. doi:10.1074/jbc.274.39.28050. PMID 10488157.
  9. ^ a b c d Lindholm CK, Henriksson ML, Hallberg B, Welsh M (Jul 2002). "Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells". European Journal of Biochemistry. 269 (13): 3279–88. doi:10.1046/j.1432-1033.2002.03008.x. PMID 12084069.

Further reading

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