List of β-lactam antibiotics

This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.

Penams edit

Narrow-spectrum edit

β-lactamase-sensitive edit

β-lactamase-resistant edit

Broad spectrum edit

Extended spectrum (Antipseudomonal) edit

Carboxypenicillins edit

Ureidopenicillins edit

Cephems edit

First generation (moderate spectrum) edit

Second generation (moderate spectrum) edit

cefuroxime, cefaclor, cefprozil

With anti-Haemophilus activity edit

With anti-anaerobic activity edit

Third generation (broad spectrum) edit

Fourth generation (broad spectrum) edit

(With β-lactamase stability and enhanced activity against Gram-positive bacteria and Pseudomonas aeruginosa)

Fifth generation* (broad spectrum) edit

(activity against MRSA and variably VRE. *Not universally accepted nomenclature. NO Antipseudomonal activity, mostly ceftriaxone coverage with additional MRSA and some VRE)

Ceftaroline, Ceftobiprole

Carbapenems and penems edit

(Broadest spectrum of β-lactam antibiotics)

Monobactams edit

Aztreonam
Tigemonam
Nocardicin A
Tabtoxinine β-lactam (does not inhibit penicillin-binding proteins)