David Edwards (engineer)

David A. Edwards (born April 6, 1961) is an American biomedical engineer, and the founder of Sensory Cloud.[1][2] He was the Gordon McKay Professor of the Practice of Biomedical Engineering at Harvard University.[3][4]

David A. Edwards
Born
David A. Edwards

(1961-04-06)April 6, 1961
Alma materMichigan Technological University, BS
Illinois Institute of Technology, PhD
Scientific career
FieldsBiomedical engineering
InstitutionsHarvard University
Websitedavidideas.com

Edwards designs inhalable medicines, vaccines and victuals.[5][6][7]

In 2001, Edwards was elected a member of the National Academy of Engineering for transfer of scientific principles of engineering to industry, including invention and commercial development of a novel, generic aerosol drug-delivery system.

Education

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Edwards studied chemical engineering, receiving a BS from Michigan Technological University in the field in 1983, and a PhD in 1987 from the Illinois Institute of Technology.[8][9]

Career

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Between 1987 and 1995, Edwards held a postdoctoral and lectureship at the Technion in Israel and the Massachusetts Institute of Technology.[10][11] While at MIT, Robert Langer, a professor at MIT, encouraged Edwards to develop an efficient way for inhalers to deliver medicine to the lungs.[12] Edwards joined the Pennsylvania State University faculty as an Associate Professor of Chemical Engineering in 1995, where he continued to research ways to make medicine inhalable.[13][14] In 1997, Science published his study on a new type of inhalable aerosol that efficiently delivered drugs to the lungs.[15][16] Edwards left academia in 1998 when he and Langer founded Advanced Inhalation Research (AIR); the startup was purchased a year later by Alkermes for $114 million.[17][18] He returned to academia in 2002, joining the Harvard faculty.[19]

Edwards' scientific work in biomedical engineering concerns the research and development of drug delivery platforms for treating infectious diseases in the developing world.[citation needed] He was a founder of Advanced Inhalation Research, now part of Alkermes, Inc.,[citation needed] of Pulmatrix,[citation needed] and of Medicine in Need, an international non-governmental organization aimed at developing new drugs and vaccines for diseases of poverty, such as tuberculosis.[20][21]

In 2020, Edwards founded the company Sensory Cloud. Sensory Cloud released a nasal inhalable product intended to reduce infected air droplets from viruses like SARS-CoV-2, a strain of coronavirus known to cause COVID-19.[22][23]

In a February 2021 study in the Proceedings of the National Academy of Sciences of the United States of America, Edwards and his colleagues posited that "exhaled aerosol increases with COVID-19 infection, age, and obesity".[24][25]

Le Laboratoire

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In 2007, Edwards opened "Le Lab" as a space for artists, designers, scientists, and the general public to meet for exhibitions, performances, and discussions in Paris,[26][27] and then he moved it to 650 East Kendall Street in the Kendall Square area of Cambridge, Massachusetts in 2014.[28][29][30] Major exhibitions by artists such as Mark Dion[31][32] and artist/engineer Chuck Hoberman[33][34] were shown, as well as innovations developed by Edwards, his associates, and his students. Some of his food-related inventions were available for purchase at Cafe ArtScience, an innovative restaurant associated with Le Laboratoire Cambridge.[35] In December 2019, it was announced that Cafe ArtScience was closing after 5 years of operation, and would be replaced by a new restaurant, called "Senses".[36]

However, the COVID-19 pandemic disrupted these plans, and as of 2022, both the restaurant and Le Laboratoire Cambridge appear to be inactive or closed, either temporarily or permanently.

Personal life

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Edwards, his wife and three children have lived alternately in Boston and Paris.[37]

Publications

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  • Edwards, David; Cantor, Jay (2008). Niche. Harvard University Press. ISBN 9780674027909.
  • Edwards, David (2009). Whiff. Harvard University Press. ISBN 9780674032866.
  • Edwards, David (2010). ArtScience: Creativity in the Post-Google Era. Harvard University Press. ISBN 978-0674034648.
  • Edwards, David (2010). The Lab: Creativity and Culture. Harvard University Press. ISBN 978-0-674-05719-7.
  • Edwards, David (2019). Creating Things That Matter: The Art and Science of Innovations That Last. Picador. ISBN 978-1-250-23071-3.
  • Edwards, D.A. (April 1994). "The macrotransport theory of nondepositing particles in the lung by convective dispersion". Journal of Aerosol Science. 25 (3): 533–565. doi:10.1016/0021-8502(94)90071-X. Retrieved 17 April 2021.
  • Edwards, D.A. (March 1995). "The macrotransport theory of lung dispersion: Aerosol deposition phenomena". Journal of Aerosol Science. 26 (2): 293–317. doi:10.1016/0021-8502(94)00101-4. Retrieved 17 April 2021.
  • Li, W. -I; Perzl, M.P.; Ferron, G.A.; Batycky, R.; Heyder, J.; Edwards, D.A. (September 1998). "The macrotransport properties of aerosol particles in the human oral-pharyngeal region". Journal of Aerosol Science. 29 (8): 995–1010. Bibcode:1998JAerS..29..995L. doi:10.1016/S0021-8502(97)10040-4. Retrieved 17 April 2021.
  • Edwards, D.A.; Chen, D.; Wang, J.; Ben-Jebria, A. (1998). "Controlled release inhalation aerosols". Resp. Drug Delivery VI: 187–192.
  • Wang, J.; Ben-Jebria, A.; Edwards, D.A. (1999). "Inhalation of estradiol for sustained systemic delivery". Journal of Aerosol Medicine. 12 (1): 27–36. doi:10.1089/jam.1999.12.27. PMID 10351127.
  • Tsapis, N.; Bennett, D.; Jackson, B.; Weitz, D.A.; Edwards, D.A. (September 2002). "Large porous carriers of nanoparticles for drug delivery". Proceedings of the National Academy of Sciences. 99 (19): 12001–12005. doi:10.1073/pnas.182233999. PMC 129387. PMID 12200546.
  • Wong, Y-L.; Sampson, S.; Germishuizen, W.; Goonesekera, S.; Caponetti, G.; Sadoff, J.; Bloom, B.R.; Edwards, D.A. (February 2007). "Drying a tuberculosis vaccine without freezing". Proceedings of the National Academy of Sciences. 104 (8): 2591–2505. Bibcode:2007PNAS..104.2591W. doi:10.1073/pnas.0611430104. PMC 1815227. PMID 17299039.

References

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  1. ^ Osgood, Charles; Braver, Rita (27 September 2015). "Does a degree in chemical engineering guarantee that its holder will enjoy the sweet smell of success?". CBS Sunday Morning. Retrieved 23 September 2020.
  2. ^ Pelekanos, Adelle C. (Spring 2008). "Creativity after Google" (PDF). New York Academy of Sciences Magazine. Retrieved 25 September 2020.
  3. ^ Bradt, Steve (13 March 2008). "Inhaled TB vaccine more effective than traditional shot". The Harvard Gazette. Retrieved 23 September 2020.
  4. ^ Etherington, Darrell (8 July 2020). "Harvard biomedical engineering professor to launch nasal spray that could reduce COVID-19 transmission risk". TechCrunch. Retrieved 23 September 2020.
  5. ^ Lazar, Kay (10 April 2009). "Need a Puff of Chocolate? Inhaler Delivers Calorie-free Mist into Your Mouth". The Boston Globe. Retrieved 23 September 2020.
  6. ^ Wilson, Mark (8 July 2020). "Harvard professor develops a $50 nasal spray to thwart the spread of COVID-19". Fast Company. Retrieved 23 September 2020.
  7. ^ Edwards, David A.; Hanes, Justin; Caponetti, Giovanni; Hrkach, Jeffrey; Ben-Jebria, Abdelaziz; Eskew, Mary Lou; Mintzes, Jeffrey; Deaver, Daniel; Lotan, Noah; Langer, Robert (20 June 1997). "Large Porous Particles for Pulmonary Drug Delivery". Science. 276 (5320): 1868–1872. doi:10.1126/science.276.5320.1868. PMID 9188534.
  8. ^ Osgood, Charles; Braver, Rita (27 September 2015). "Does a degree in chemical engineering guarantee that its holder will enjoy the sweet smell of success?". CBS Sunday Morning. Retrieved 23 September 2020.
  9. ^ Schmadeke, Steve (10 April 2009). "A whiff of innovation--and chocolate". Chicago Tribune. Retrieved 24 September 2020.
  10. ^ "The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006". MIT. Retrieved 25 September 2020.
  11. ^ Legg, Heidi (29 September 2015). "The Scent of a Cyborg". TheEditorial. Retrieved 25 September 2020.
  12. ^ Aoki, Naomi (25 May 2003). "MIT Scientist Sees Science As Means to Change the World and He Has". The Boston Globe.
  13. ^ Aoki, Naomi (25 May 2003). "MIT Scientist Sees Science As Means to Change the World and He Has". The Boston Globe.
  14. ^ "The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006". MIT. Retrieved 25 September 2020.
  15. ^ Scripps News Service (20 June 1997). "New aerosol particle helps fight lung disorders". Deseret News. Retrieved 29 September 2020.
  16. ^ Edwards, David; Hanes, J; Caponetti, G; Hrkach, J; Ben-Jebria, A; Eskew, M.L.; Mintzes, J; Deaver, D; Lotan, N; Langer, R (20 June 1997). "Large porous particles for pulmonary drug delivery". Science. 276 (5320): 1868–1871. doi:10.1126/science.276.5320.1868. PMID 9188534.
  17. ^ Kirsner, Scott (3 March 2013). "Harvard dreamer looks for ways to link art, science, and commerce: Innovation Economy". The Boston Globe. Retrieved 23 September 2020.
  18. ^ Aoki, Naomi (25 May 2003). "MIT Scientist Sees Science As Means to Change the World and He Has". The Boston Globe.
  19. ^ "The Alan S. Michaels Distinguished Lectureship in Medical and Biological Engineering – 2006". MIT. Retrieved 25 September 2020.
  20. ^ "Chutzpah Science", Forbes, May 25, 2005.
  21. ^ "Nose Spray May Slow Spread of Germs", Fox News, November 30, 2004.
  22. ^ Wilson, Mark (8 July 2020). "Harvard professor develops a $50 nasal spray to thwart the spread of COVID-19". Fast Company. Retrieved 23 September 2020.
  23. ^ "The Best Inventions of 2020: 100 innovations changing how we live". Time. 19 November 2020. Retrieved 25 August 2021.
  24. ^ Edwards, David (23 February 2021). "Exhaled aerosol increases with COVID-19 infection, age, and obesity". Proceedings of the National Academy of Sciences of the United States of America. 118 (8): e2021830118. Bibcode:2021PNAS..11821830E. doi:10.1073/pnas.2021830118. PMC 7923364. PMID 33563754.
  25. ^ Hussein, Tareq; Löndahl, Jakob; Thuresson, Sara; Alsved, Malin; Al-Hunaiti, Afnan; Saksela, Kalle; Aqel, Hazem; Junninen, Heikki; Mahura, Alexander; Kulmalla, Markku (12 March 2021). "Indoor Model Simulation for COVID-19 Transport and Exposure". Int. J. Environ. Res. Public Health. 18 (6): 2927. doi:10.3390/ijerph18062927. PMC 7999367. PMID 33809366.
  26. ^ Dessent, Blaire. "December 2007, Le Laboratoire". Whitehot Magazine of Contemporary Art. Retrieved 2022-12-31.
  27. ^ Kirsner, Scott (April 1, 2013). "Accelerating art, science in Lab Cambridge". Boston Globe. Retrieved 2023-01-01.
  28. ^ "Le Laboratoire Cambridge". C.E. Floyd. C.E. Floyd Company, PBC. Retrieved 2022-12-31.
  29. ^ Zoia, Gabriella (5 November 2014). "Le Laboratoire creates interactive space for groundbreaking innovation in art, science". The Tufts Daily. Retrieved 2023-01-24.
  30. ^ Lau, Cat (April 24, 2017). "SPACES – Le Laboratoire Cambridge". Polyfield Magazine. Retrieved 2023-01-24.
  31. ^ Gayla, Marella A (November 5, 2015). "The Trouble with Jellyfish". The Harvard Crimson. Retrieved 2022-12-31.
  32. ^ "'The Trouble with Jellyfish'". Harvard Gazette. Harvard University. 26 October 2015. Retrieved 2022-12-31.
  33. ^ Phongsirivech, Pimploy (26 October 2016). "See Transformable Structures at Le Lab Cambridge". Boston Magazine. Retrieved 2023-01-01.
  34. ^ "10° (Ten Degrees)". Hoberman Associates. Retrieved 2023-01-01.
  35. ^ Jiang, Nancy (September 19, 2019). "Cambridge Café ArtScience explores the future of food". The Daily Free Press. Retrieved 2023-01-01.
  36. ^ Blumenthal, Rachel Leah (20 December 2019). "Cafe Artscience Is Closing in Cambridge After Five Years". Eater Boston. Retrieved 2023-01-01.
  37. ^ Kirsner, Scott (3 March 2013). "Harvard dreamer looks for ways to link art, science, and commerce: Innovation Economy". The Boston Globe. Retrieved 23 September 2020.
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