43 may refer to:
- 43 (number)
- one of the years 43 BC, AD 43, 1943, 2043
- Licor 43, also known as "Cuarenta Y Tres" ("Forty-three" in Spanish)
- George W. Bush, 43rd president of the United States, nicknamed "Bush 43" to distinguish from his father
- "Forty Three", a song by Karma to Burn from the album Appalachian Incantation, 2010
- 43 Ariadne, a main-belt asteroid
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